1-Hydroxy-cyclobutanecarboxylic acid
1-Hydroxy-cyclobutanecarboxylic acid
CAS: 41248-13-9
Molecular Formula: C5H8O3
1-Hydroxy-cyclobutanecarboxylic acid - Names and Identifiers
| Name | 1-Hydroxy-cyclobutanecarboxylic acid |
| Synonyms | 1-Hydroxy-cyclobutanecarboxylic acid 1-hydroxycyclobutane-1-carboxylicacid Cyclobutanecarboxylic acid, 1-hydroxy- |
| CAS | 41248-13-9 |
1-Hydroxy-cyclobutanecarboxylic acid - Physico-chemical Properties
| Molecular Formula | C5H8O3 |
| Molar Mass | 116.12 |
| Density | 1.476±0.06 g/cm3(Predicted) |
| Melting Point | 68 °C(Solv: benzene (71-43-2); ligroine (8032-32-4)) |
| Boling Point | 120 °C |
| pKa | 4.05±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD08861856 |
1-Hydroxy-cyclobutanecarboxylic acid - Upstream Downstream Industry
| Downstream Products | NSC62079 |
1-Hydroxy-cyclobutanecarboxylic acid - Introduction
Acid is an organic compound with the chemical formula C5H8O3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: acid white crystals or crystalline solid powder.
-Solubility: It is slightly soluble in water and can be dissolved in organic solvents such as ethanol, ether and acetone.
-Melting point: about 105-107 degrees Celsius.
Use:
-Chemical synthesis: acid can be used as an important intermediate in organic synthesis, and has a wide range of applications in the fields of drugs and pesticides.
-Drug research: It can be used as a precursor or raw material of drug molecules in the field of drug research, and is used to synthesize biologically active compounds.
Preparation Method:
The acid can be synthesized by the following methods:
-Cyclobutanone is reacted with sodium cyanide to obtain hydroxynitrile.
-Hydroxy nitrile reacts with aluminum chloride to produce hydroxy cyclobutyronitrile.
-Hydroxycyclobutyronitrile reacts with hydrochloric acid to produce 1-Hydroxycyclobutyronitrile hydrochloride.
-acid 1-hydroxycyclobutyronitrile hydrochloride by acidolysis.
Safety Information:
-no acid belongs to chemicals, and safety operation regulations shall be observed during use.
-It may cause irritation to the eyes, skin and respiratory tract, so the necessary protective measures should be taken when exposed.
-Avoid inhaling dust and skin contact during use.
-When storing and handling, it needs to be stored in a closed container, away from fire and oxidizing agents.
-If accidental contact or ingestion occurs, seek medical attention immediately.
Nature:
-Appearance: acid white crystals or crystalline solid powder.
-Solubility: It is slightly soluble in water and can be dissolved in organic solvents such as ethanol, ether and acetone.
-Melting point: about 105-107 degrees Celsius.
Use:
-Chemical synthesis: acid can be used as an important intermediate in organic synthesis, and has a wide range of applications in the fields of drugs and pesticides.
-Drug research: It can be used as a precursor or raw material of drug molecules in the field of drug research, and is used to synthesize biologically active compounds.
Preparation Method:
The acid can be synthesized by the following methods:
-Cyclobutanone is reacted with sodium cyanide to obtain hydroxynitrile.
-Hydroxy nitrile reacts with aluminum chloride to produce hydroxy cyclobutyronitrile.
-Hydroxycyclobutyronitrile reacts with hydrochloric acid to produce 1-Hydroxycyclobutyronitrile hydrochloride.
-acid 1-hydroxycyclobutyronitrile hydrochloride by acidolysis.
Safety Information:
-no acid belongs to chemicals, and safety operation regulations shall be observed during use.
-It may cause irritation to the eyes, skin and respiratory tract, so the necessary protective measures should be taken when exposed.
-Avoid inhaling dust and skin contact during use.
-When storing and handling, it needs to be stored in a closed container, away from fire and oxidizing agents.
-If accidental contact or ingestion occurs, seek medical attention immediately.
Last Update：2024-04-09 20:49:11
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